Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
hypothetical protein	HMPREF0837_RS09670	Not Available	Negative	1851105 - 1851284	6995.27
hypothetical protein	HMPREF0837_RS09675	Not Available	Negative	1851449 - 1851688	9396.25
replication-associated recombination protein a	HMPREF0837_RS09680	Not Available	Positive	1851958 - 1853229	47002.1
Trna-lys	Not Available	Not Available	Positive	1853494 - 1853566	Not Available
glycoside hydrolase family 32 protein	HMPREF0837_RS09690	Not Available	Negative	1853776 - 1855095	51291.2
abc transporter substrate-binding protein	HMPREF0837_RS09695	Not Available	Negative	1855105 - 1856721	61082.6
carbohydrate abc transporter permease	HMPREF0837_RS09700	Not Available	Negative	1856750 - 1857640	33558.3
abc transporter permease	HMPREF0837_RS09705	Not Available	Negative	1857651 - 1858568	33919.6
laci family dna-binding transcriptional regulator	HMPREF0837_RS09710	Not Available	Negative	1858719 - 1859720	37730.4
virulence factor transcriptional regulator mgaspn	HMPREF0837_RS09715	Not Available	Negative	1860082 - 1861563	58758.4