Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
16s rrna (uracil(1498)-n(3))-methyltransferase	HMPREF0837_RS09620	Not Available	Negative	1842127 - 1842870	27168.9
50s ribosomal protein l11 methyltransferase	HMPREF0837_RS09625	Not Available	Negative	1842872 - 1843822	34749.3
abih family protein	HMPREF0837_RS09630	Not Available	Negative	1843837 - 1844853	39373.5
s8 family peptidase	HMPREF0837_RS09635	Not Available	Negative	1844904 - 1847087	81988.2
atp-binding protein	HMPREF0837_RS09640	Not Available	Negative	1847149 - 1848183	39028.1
hypothetical protein	HMPREF0837_RS09645	Not Available	Negative	1848302 - 1848451	5566.76
site-2 protease family protein	HMPREF0837_RS09650	Not Available	Negative	1848432 - 1849520	41083.4
duf3013 family protein	HMPREF0837_RS09655	Not Available	Negative	1849539 - 1850009	18078.9
type ii toxin-antitoxin system hicb family antitoxin	HMPREF0837_RS09660	Not Available	Negative	1850300 - 1850752	16660.3
type ii toxin-antitoxin system hica family toxin	HMPREF0837_RS09665	Not Available	Negative	1850789 - 1850968	6714.41