Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
class i sam-dependent dna methyltransferase	HMPREF0837_RS09510	Not Available	Negative	1827147 - 1827887	28421.0
ribosome silencing factor	HMPREF0837_RS09515	Not Available	Negative	1827996 - 1828349	12854.2
cysteine hydrolase family protein	HMPREF0837_RS09520	Not Available	Negative	1828362 - 1828862	19197.8
bis(5'-nucleosyl)-tetraphosphatase (symmetrical) yqek	HMPREF0837_RS09525	Not Available	Negative	1828863 - 1829456	22564.8
nicotinate-nucleotide adenylyltransferase	HMPREF0837_RS09530	Not Available	Negative	1829456 - 1830085	24254.6
ribosome assembly rna-binding protein yhby	HMPREF0837_RS09535	Not Available	Negative	1830137 - 1830448	11705.3
ribosome biogenesis gtpase yqeh	HMPREF0837_RS09540	Not Available	Negative	1830662 - 1831768	40971.6
yqeg family had iiia-type phosphatase	HMPREF0837_RS09545	Not Available	Negative	1831771 - 1832298	20101.5
magnesium transporter cora family protein	HMPREF0837_RS09550	Not Available	Negative	1832313 - 1833221	34684.9
mechanosensitive ion channel family protein	HMPREF0837_RS09555	Not Available	Negative	1833278 - 1833838	20721.9