Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
pts sugar transporter subunit iib	HMPREF0837_RS00890	Not Available	Negative	165018 - 165488	18048.1
pts sugar transporter subunit iia	HMPREF0837_RS00895	Not Available	Negative	165479 - 165910	15906.9
rbsd/fucu family protein	HMPREF0837_RS00900	Not Available	Negative	165903 - 166343	16427.9
l-fuculose-phosphate aldolase	HMPREF0837_RS00905	Not Available	Negative	166355 - 166993	23653.5
rhamnulokinase	HMPREF0837_RS00910	Not Available	Negative	167108 - 168511	52854.2
deor/glpr family dna-binding transcription regulator	HMPREF0837_RS00915	Not Available	Positive	168687 - 169460	29299.1
zinc abc transporter substrate-binding lipoprotein adca	HMPREF0837_RS00920	Not Available	Negative	170631 - 172136	56258.9
metal abc transporter permease	HMPREF0837_RS00925	Not Available	Negative	172146 - 172952	28891.7
metal abc transporter atp-binding protein	HMPREF0837_RS00930	Not Available	Negative	172945 - 173649	26527.3
zinc-dependent transcriptional regulator adcr	HMPREF0837_RS00935	Not Available	Negative	173649 - 174089	16606.9