Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
cell division protein diviva	HMPREF0837_RS09105	Not Available	Negative	1744385 - 1745173	30186.4
rna-binding protein	HMPREF0837_RS09110	Not Available	Negative	1745182 - 1745967	30407.0
yggt family protein	HMPREF0837_RS09115	Not Available	Negative	1745964 - 1746227	9764.54
cell division protein sepf	HMPREF0837_RS09120	Not Available	Negative	1746227 - 1746766	20638.3
yggs family pyridoxal phosphate-dependent enzyme	HMPREF0837_RS09125	Not Available	Negative	1746776 - 1747447	25568.8
cell division protein ftsz	HMPREF0837_RS09130	Not Available	Negative	1747452 - 1748711	44418.6
cell division protein ftsa	HMPREF0837_RS09135	Not Available	Negative	1748728 - 1750101	49477.8
tigr02206 family membrane protein	HMPREF0837_RS09140	Not Available	Negative	1750320 - 1751024	26956.5
nudix hydrolase n-terminal domain-containing protein	HMPREF0837_RS09145	Not Available	Negative	1751115 - 1751726	23507.8
udp-n-acetylmuramoyl-tripeptide--d-alanyl-d- alanine ligase	HMPREF0837_RS09150	Not Available	Negative	1751713 - 1753086	50519.4