Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
metal abc transporter permease	HMPREF0837_RS09040	Not Available	Positive	1730591 - 1731439	30188.3
metal abc transporter substrate-binding lipoprotein/adhesin psaa	HMPREF0837_RS09045	Not Available	Positive	1731471 - 1732400	34596.1
thiol peroxidase	HMPREF0837_RS09050	Not Available	Positive	1732523 - 1733014	18020.4
abc transporter permease	HMPREF0837_RS09055	Not Available	Negative	1733110 - 1735818	100465.0
abc transporter atp-binding protein	HMPREF0837_RS09060	Not Available	Negative	1735820 - 1736521	25736.6
glycosyl hydrolase family 95 catalytic domain-containing protein	HMPREF0837_RS09065	Not Available	Negative	1736771 - 1739182	91568.4
phosphoglycerate mutase	HMPREF0837_RS09070	Not Available	Negative	1739235 - 1739927	26051.7
hypothetical protein	HMPREF0837_RS12755	Not Available	Negative	1739978 - 1740268	11249.4
hypothetical protein	HMPREF0837_RS09085	Not Available	Negative	1740462 - 1740842	12722.3
isoleucine--trna ligase	HMPREF0837_RS09090	Not Available	Negative	1741245 - 1744037	105127.0