Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
mazg-like protein	HMPREF0837_RS08935	Not Available	Positive	1712002 - 1712178	7152.51
threonine--trna ligase	HMPREF0837_RS08940	Not Available	Positive	1712236 - 1714179	74687.5
hamp domain-containing histidine kinase	HMPREF0837_RS08945	Not Available	Negative	1714228 - 1715202	38100.6
response regulator transcription factor	HMPREF0837_RS08950	Not Available	Negative	1715195 - 1715872	25965.7
duf2974 domain-containing protein	HMPREF0837_RS08955	Not Available	Positive	1716028 - 1717101	41088.2
hypothetical protein	HMPREF0837_RS08960	Not Available	Negative	1717192 - 1717494	11902.9
rrf2 family transcriptional regulator	HMPREF0837_RS08965	Not Available	Negative	1717562 - 1717999	15837.3
metallophosphoesterase family protein	HMPREF0837_RS08970	Not Available	Negative	1718075 - 1718917	32407.7
metal-dependent transcriptional regulator	HMPREF0837_RS08975	Not Available	Positive	1719029 - 1719679	24827.0
hypothetical protein	HMPREF0837_RS13375	Not Available	Positive	1719660 - 1719851	7414.1