Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
fructose pts transporter subunit iia	HMPREF0837_RS08885	Not Available	Negative	1702167 - 1702616	16360.5
pts sugar transporter subunit iia	HMPREF0837_RS08890	Not Available	Negative	1702594 - 1703022	16462.0
bglg family transcription antiterminator	HMPREF0837_RS08895	Not Available	Negative	1703015 - 1704478	56148.3
cation-translocating p-type atpase	HMPREF0837_RS08900	Not Available	Negative	1705007 - 1707343	85431.3
lysophospholipid acyltransferase family protein	HMPREF0837_RS08905	Not Available	Positive	1707476 - 1708225	28935.4
cadd family cadmium resistance transporter	HMPREF0837_RS08910	Not Available	Negative	1708518 - 1709132	22849.3
30s ribosomal protein s15	HMPREF0837_RS08915	Not Available	Negative	1709948 - 1710217	10535.8
nad(p)-dependent oxidoreductase	HMPREF0837_RS08920	Not Available	Negative	1710358 - 1710987	22929.2
hypothetical protein	HMPREF0837_RS08925	Not Available	Positive	1711225 - 1711425	8208.36
mazg-like protein	HMPREF0837_RS08930	Not Available	Positive	1711855 - 1711995	5569.49