Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
mfs transporter	HMPREF0837_RS08790	Not Available	Negative	1685911 - 1687062	41699.7
pr6pr family membrane protein	HMPREF0837_RS08795	Not Available	Negative	1687302 - 1687931	24620.0
zinc ribbon domain-containing protein yjdm	HMPREF0837_RS08800	Not Available	Negative	1687934 - 1688272	12315.7
(d)cmp kinase	HMPREF0837_RS08805	Not Available	Negative	1688403 - 1689074	24641.5
sag1386/ef1546 family surface-associated protein	HMPREF0837_RS08810	Not Available	Negative	1689083 - 1689559	16870.7
ferredoxin	HMPREF0837_RS12015	Not Available	Positive	1689611 - 1689817	7706.1
glycosyltransferase family 2 protein	HMPREF0837_RS08820	Not Available	Negative	1689868 - 1690833	36512.8
udp-glucose 4-epimerase gale	HMPREF0837_RS08825	Not Available	Negative	1690835 - 1691854	37436.5
hypothetical protein	HMPREF0837_RS13210	Not Available	Negative	1691957 - 1692085	4995.73
nad(p)/fad-dependent oxidoreductase	HMPREF0837_RS08835	Not Available	Negative	1692155 - 1693258	40614.6