Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
zmpa/zmpb/zmpc family metallo-endopeptidase	HMPREF0837_RS00840	Not Available	Negative	152943 - 153158	8196.85
ysirk-type signal peptide-containing protein	HMPREF0837_RS00845	Not Available	Negative	153146 - 153397	9699.55
hypothetical protein	HMPREF0837_RS12830	Not Available	Positive	153601 - 153768	6225.26
spfh domain-containing protein	HMPREF0837_RS00855	Not Available	Negative	153795 - 154679	32986.1
iron-containing alcohol dehydrogenase	HMPREF0837_RS00860	Not Available	Negative	154824 - 155975	41238.8
l-fucose isomerase	HMPREF0837_RS00865	Not Available	Negative	156121 - 157887	65742.3
glycosyl hydrolase family 98 c-terminal domain-containing protein	HMPREF0837_RS00870	Not Available	Negative	157944 - 161060	117715.0
glycosyl hydrolase family 95 catalytic domain-containing protein	HMPREF0837_RS00875	Not Available	Negative	161070 - 163364	87407.0
pts system mannose/fructose/sorbose family transporter subunit iid	HMPREF0837_RS00880	Not Available	Negative	163423 - 164223	28983.5
pts mannose/fructose/sorbose/n-acetylgalactosamine transporter subunit iic	HMPREF0837_RS00885	Not Available	Negative	164220 - 164993	27192.8