Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
yvck family protein	HMPREF0837_RS08630	Not Available	Negative	1658538 - 1659515	36061.5
rnase adapter rapz	HMPREF0837_RS08635	Not Available	Negative	1659512 - 1660402	33768.5
rida family protein	HMPREF0837_RS08640	Not Available	Negative	1660454 - 1660834	13732.4
ribosome biogenesis gtp-binding protein yiha/ysxc	HMPREF0837_RS08645	Not Available	Negative	1660845 - 1661432	22274.7
atp-dependent clp protease atp-binding subunit clpx	HMPREF0837_RS08650	Not Available	Negative	1661441 - 1662673	45728.0
hypothetical protein	HMPREF0837_RS08655	Not Available	Negative	1662710 - 1662880	6440.14
dihydrofolate reductase	HMPREF0837_RS08660	Not Available	Negative	1662880 - 1663386	19731.5
dps family protein	HMPREF0837_RS08665	Not Available	Negative	1663518 - 1664036	19311.0
choline binding-anchored murein hydrolase lytc	HMPREF0837_RS08670	Not Available	Negative	1664533 - 1666038	58705.0
triose-phosphate isomerase	HMPREF0837_RS08675	Not Available	Negative	1666076 - 1666834	26551.5