Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
abc-f family atp-binding cassette domain-containing protein	HMPREF0837_RS08575	Not Available	Negative	1648087 - 1649958	70967.7
cca trna nucleotidyltransferase	HMPREF0837_RS08580	Not Available	Negative	1649955 - 1651154	45755.3
4-hydroxy-tetrahydrodipicolinate reductase	HMPREF0837_RS08585	Not Available	Negative	1651151 - 1651918	27838.3
degv family protein	HMPREF0837_RS08590	Not Available	Negative	1652195 - 1653043	30977.0
duf1149 family protein	HMPREF0837_RS08595	Not Available	Negative	1653045 - 1653419	14414.0
phosphoglucosamine mutase	HMPREF0837_RS08600	Not Available	Negative	1653493 - 1654845	48126.4
ybbr-like domain-containing protein	HMPREF0837_RS08605	Not Available	Negative	1654869 - 1655648	27879.0
diadenylate cyclase cdaa	HMPREF0837_RS08610	Not Available	Negative	1655635 - 1656492	31855.2
nad(p)/fad-dependent oxidoreductase	HMPREF0837_RS08620	Not Available	Positive	1656628 - 1657596	35271.0
dna-binding protein whia	HMPREF0837_RS08625	Not Available	Negative	1657630 - 1658541	34093.8