Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
nadph-dependent fmn reductase	HMPREF0837_RS08525	Not Available	Positive	1631629 - 1632177	19782.6
ysirk signal domain/lpxtg anchor domain surface protein	HMPREF0837_RS08530	Not Available	Negative	1632414 - 1638035	197098.0
m protein trans-acting positive regulator prd domain-containing protein	HMPREF0837_RS08535	Not Available	Positive	1638251 - 1639735	58936.6
peroxide stress protein yaaa	HMPREF0837_RS08540	Not Available	Negative	1639786 - 1640514	27467.4
yczi family protein	HMPREF0837_RS08545	Not Available	Negative	1640593 - 1640757	5946.69
hypothetical protein	HMPREF0837_RS08550	Not Available	Negative	1640823 - 1642418	59427.1
peptide deformylase	HMPREF0837_RS08555	Not Available	Negative	1642430 - 1642840	15372.7
glutathione-dependent disulfide-bond oxidoreductase	HMPREF0837_RS08560	Not Available	Negative	1642956 - 1643747	29482.0
cation-translocating p-type atpase	HMPREF0837_RS08565	Not Available	Negative	1643760 - 1646456	97029.7
cdf family manganese efflux transporter mnte	HMPREF0837_RS08570	Not Available	Positive	1646760 - 1647944	44508.6