Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
trna1(val) (adenine(37)-n6)-methyltransferase	HMPREF0837_RS08470	Not Available	Negative	1623861 - 1624610	28324.1
s1 rna-binding domain-containing protein	HMPREF0837_RS08475	Not Available	Negative	1624664 - 1625023	13878.7
bifunctional cof-type had-iib family hydrolase/peptidylprolyl isomerase	HMPREF0837_RS08480	Not Available	Negative	1625025 - 1626425	52047.7
30s ribosomal protein s18	HMPREF0837_RS08485	Not Available	Negative	1626720 - 1626959	9204.3
single-stranded dna-binding protein ssba	HMPREF0837_RS08490	Not Available	Negative	1626991 - 1627461	17352.2
30s ribosomal protein s6	HMPREF0837_RS08495	Not Available	Negative	1627473 - 1627763	11153.3
asparagine--trna ligase	HMPREF0837_RS08500	Not Available	Negative	1627916 - 1629259	51069.6
hypothetical protein	HMPREF0837_RS13365	Not Available	Negative	1629278 - 1629643	13466.8
pyridoxal phosphate-dependent aminotransferase	HMPREF0837_RS08510	Not Available	Negative	1629636 - 1630823	43061.2
duf5590 domain-containing protein	HMPREF0837_RS08515	Not Available	Negative	1630820 - 1631308	18321.9