Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
hypothetical protein	HMPREF0837_RS13060	Not Available	Negative	1585051 - 1585896	32227.3
phospho-sugar mutase	HMPREF0837_RS08275	Not Available	Positive	1586130 - 1587848	62676.0
thioredoxin	HMPREF0837_RS08280	Not Available	Positive	1587959 - 1588306	12881.3
amino acid abc transporter substrate-binding protein	HMPREF0837_RS08285	Not Available	Negative	1588585 - 1589421	31024.4
amino acid abc transporter atp-binding protein	HMPREF0837_RS08290	Not Available	Negative	1589434 - 1590063	23146.3
amino acid abc transporter permease	HMPREF0837_RS08295	Not Available	Negative	1590073 - 1590714	23968.2
tetratricopeptide repeat protein	HMPREF0837_RS08300	Not Available	Negative	1590860 - 1592089	47495.1
ai-2e family transporter	HMPREF0837_RS08305	Not Available	Negative	1592079 - 1593245	43286.5
lactonase family protein	HMPREF0837_RS08310	Not Available	Positive	1593389 - 1594402	37728.9
f0f1 atp synthase subunit epsilon	HMPREF0837_RS08315	Not Available	Negative	1594447 - 1594866	15638.8