Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
abc transporter permease	HMPREF0837_RS08170	Not Available	Negative	1568434 - 1569693	45293.1
abc transporter atp-binding protein	HMPREF0837_RS08175	Not Available	Negative	1569695 - 1570396	25744.1
efflux rnd transporter periplasmic adaptor subunit	HMPREF0837_RS08180	Not Available	Negative	1570380 - 1571579	41885.8
glutathione-disulfide reductase	HMPREF0837_RS08185	Not Available	Positive	1571865 - 1573211	48846.1
biotin transporter bioy	HMPREF0837_RS08190	Not Available	Positive	1573408 - 1573944	18603.4
hypothetical protein	HMPREF0837_RS13055	Not Available	Positive	1574007 - 1574153	5640.63
ydbc family protein	HMPREF0837_RS08200	Not Available	Negative	1574150 - 1574365	8122.52
hypothetical protein	HMPREF0837_RS08205	Not Available	Positive	1574463 - 1574783	12348.7
atp cone domain-containing protein	HMPREF0837_RS08210	Not Available	Negative	1574813 - 1575151	12937.7
trna (guanosine(37)-n1)-methyltransferase trmd	HMPREF0837_RS08215	Not Available	Negative	1575163 - 1575882	27634.8