Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
dna topoisomerase (atp-hydrolyzing) subunit b	HMPREF0837_RS08065	Not Available	Negative	1547571 - 1549517	72271.7
had family hydrolase	HMPREF0837_RS08070	Not Available	Negative	1549532 - 1550095	21134.9
dj-1 family glyoxalase iii	HMPREF0837_RS08075	Not Available	Negative	1550180 - 1550734	20155.0
ftsw/roda/spove family cell cycle protein	HMPREF0837_RS08080	Not Available	Negative	1550745 - 1551968	45237.1
bifunctional dnaq family exonuclease/atp-dependent helicase	HMPREF0837_RS08085	Not Available	Negative	1552005 - 1554455	93511.4
peptidase u32 family protein	HMPREF0837_RS08095	Not Available	Negative	1554655 - 1555584	35589.3
duf3270 domain-containing protein	HMPREF0837_RS08100	Not Available	Positive	1555724 - 1556011	11000.6
two-component system sensor histidine kinase ciah	HMPREF0837_RS08105	Not Available	Negative	1556045 - 1557379	50676.3
two-component system response regulator ciar	HMPREF0837_RS08110	Not Available	Negative	1557369 - 1558043	25467.8
m1 family metallopeptidase	HMPREF0837_RS08115	Not Available	Negative	1558152 - 1560698	95302.3