Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
thiol-activated cytolysin c-terminal domain-containing protein	HMPREF0837_RS07945	Not Available	Negative	1528017 - 1528529	19458.2
hypothetical protein	HMPREF0837_RS07950	Not Available	Negative	1528554 - 1529128	21524.2
lipase family protein	HMPREF0837_RS07955	Not Available	Negative	1529138 - 1529533	14809.5
purine-nucleoside phosphorylase	HMPREF0837_RS07960	Not Available	Negative	1530009 - 1530818	29005.1
duf1697 domain-containing protein	HMPREF0837_RS07965	Not Available	Negative	1530834 - 1531376	20852.2
phosphopentomutase	HMPREF0837_RS07970	Not Available	Negative	1531378 - 1532589	44079.2
ribose-5-phosphate isomerase rpia	HMPREF0837_RS07975	Not Available	Negative	1532603 - 1533286	24793.8
nad(p)h-hydrate dehydratase	HMPREF0837_RS07980	Not Available	Negative	1533568 - 1534440	31638.4
bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	HMPREF0837_RS07985	Not Available	Negative	1534582 - 1535439	30721.6
amino acid abc transporter atp-binding protein	HMPREF0837_RS07990	Not Available	Negative	1535593 - 1536327	27092.1