Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
bmp family protein	HMPREF0837_RS07895	Not Available	Negative	1519966 - 1521018	36801.8
cytidine deaminase	HMPREF0837_RS07900	Not Available	Negative	1521109 - 1521498	14216.0
deoxyribose-phosphate aldolase	HMPREF0837_RS07905	Not Available	Negative	1521485 - 1522147	23074.7
pyrimidine-nucleoside phosphorylase	HMPREF0837_RS07910	Not Available	Negative	1522165 - 1523442	46177.1
class i sam-dependent methyltransferase	HMPREF0837_RS07915	Not Available	Negative	1523439 - 1524029	21742.4
hypothetical protein	HMPREF0837_RS13355	Not Available	Negative	1524236 - 1524639	14657.2
type i pantothenate kinase	HMPREF0837_RS07925	Not Available	Positive	1524829 - 1525749	35557.2
30s ribosomal protein s20	HMPREF0837_RS07930	Not Available	Positive	1525817 - 1526053	8556.31
dna topology modulation protein	HMPREF0837_RS07935	Not Available	Positive	1526106 - 1526630	21122.3
purine-nucleoside phosphorylase	HMPREF0837_RS07940	Not Available	Negative	1526653 - 1527363	26127.3