Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
peptide abc transporter substrate-binding protein	HMPREF0837_RS07835	Not Available	Negative	1507351 - 1508055	25923.7
branched-chain amino acid aminotransferase	HMPREF0837_RS07840	Not Available	Negative	1508111 - 1509133	37487.6
dna topoisomerase iv subunit a	HMPREF0837_RS07845	Not Available	Negative	1509265 - 1511736	93126.3
hypothetical protein	HMPREF0837_RS13205	Not Available	Negative	1511937 - 1512141	7315.69
dna topoisomerase iv subunit b	HMPREF0837_RS07855	Not Available	Negative	1512156 - 1514099	71639.4
glycerol-3-phosphate 1-o-acyltransferase plsy	HMPREF0837_RS07860	Not Available	Positive	1514235 - 1514876	22958.9
hypothetical protein	HMPREF0837_RS07865	Not Available	Negative	1514921 - 1516192	49775.1
abc transporter permease	HMPREF0837_RS07880	Not Available	Negative	1516277 - 1517233	33751.0
abc transporter permease	HMPREF0837_RS07885	Not Available	Negative	1517236 - 1518294	37420.8
abc transporter atp-binding protein	HMPREF0837_RS07890	Not Available	Negative	1518287 - 1519822	55138.8