Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
duf3272 domain-containing protein	HMPREF0837_RS07785	Not Available	Negative	1500585 - 1500779	7721.5
dna polymerase iii subunit gamma/tau	HMPREF0837_RS07790	Not Available	Negative	1500807 - 1502462	60876.7
gaf domain-containing protein	HMPREF0837_RS07795	Not Available	Negative	1502462 - 1502959	18422.1
30s ribosomal protein s1	HMPREF0837_RS07800	Not Available	Negative	1503045 - 1504247	43898.3
Trna-gln	Not Available	Not Available	Positive	1504409 - 1504480	Not Available
Trna-tyr	Not Available	Not Available	Positive	1504490 - 1504570	Not Available
duf2969 domain-containing protein	HMPREF0837_RS07815	Not Available	Negative	1504620 - 1504850	8494.3
pyroglutamyl-peptidase i	HMPREF0837_RS07820	Not Available	Negative	1505018 - 1505662	23421.4
duf979 domain-containing protein	HMPREF0837_RS07825	Not Available	Negative	1505677 - 1506600	32777.5
duf969 domain-containing protein	HMPREF0837_RS07830	Not Available	Negative	1506597 - 1507286	24974.9