Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
deor/glpr family dna-binding transcription regulator	HMPREF0837_RS07735	Not Available	Negative	1490417 - 1491157	27286.9
Trna-ser	Not Available	Not Available	Positive	1491320 - 1491407	Not Available
Tmrna,resume consensus sequence (at 76): tataactgcaaaaaataa	Not Available	Not Available	Positive	1491603 - 1491947	Not Available
cell elongation protein coze	HMPREF0837_RS07745	Not Available	Negative	1492593 - 1493702	41481.8
d-alanyl-d-alanine carboxypeptidase pbp3	HMPREF0837_RS07750	Not Available	Positive	1493805 - 1495046	45172.6
fe-s cluster assembly protein sufb	HMPREF0837_RS07760	Not Available	Negative	1495245 - 1496657	52707.3
fe-s cluster assembly sulfur transfer protein sufu	HMPREF0837_RS07765	Not Available	Negative	1496711 - 1497151	15958.0
cysteine desulfurase	HMPREF0837_RS07770	Not Available	Negative	1497138 - 1498364	45196.9
fe-s cluster assembly protein sufd	HMPREF0837_RS07775	Not Available	Negative	1498375 - 1499637	46298.8
fe-s cluster assembly atpase sufc	HMPREF0837_RS07780	Not Available	Negative	1499665 - 1500435	28407.5