Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
phoh family protein	HMPREF0837_RS07385	Not Available	Negative	1418442 - 1419410	36287.2
yoze family protein	HMPREF0837_RS07390	Not Available	Negative	1419496 - 1419711	8419.68
rna-binding virulence regulatory protein cvfb	HMPREF0837_RS07395	Not Available	Negative	1419720 - 1420574	32378.0
ribosome recycling factor	HMPREF0837_RS07400	Not Available	Negative	1420634 - 1421191	20657.8
ump kinase	HMPREF0837_RS07405	Not Available	Negative	1421200 - 1421937	26434.8
methylenetetrahydrofolate--trna-(uracil(54)- c(5))-methyltransferase (fadh(2)-oxidizing) trmfo	HMPREF0837_RS07410	Not Available	Negative	1422021 - 1423355	49302.9
16s rrna (cytidine(1402)-2'-o)-methyltransferase	HMPREF0837_RS07415	Not Available	Negative	1423542 - 1424420	32929.9
dna replication initiation control protein yaba	HMPREF0837_RS07420	Not Available	Negative	1424423 - 1424740	12411.7
dna polymerase iii subunit delta'	HMPREF0837_RS07425	Not Available	Negative	1424780 - 1425670	34342.9
dtmp kinase	HMPREF0837_RS07430	Not Available	Negative	1425667 - 1426305	23370.3