Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
translation initiation factor if-3	HMPREF0837_RS07325	Not Available	Negative	1409312 - 1409842	20084.7
membrane protein	HMPREF0837_RS07330	Not Available	Negative	1410149 - 1411330	44816.3
atp-binding cassette domain-containing protein	HMPREF0837_RS07335	Not Available	Negative	1411334 - 1411921	22790.7
hypothetical protein	HMPREF0837_RS07340	Not Available	Negative	1411954 - 1412178	8869.15
dna internalization-related competence protein comec/rec2	HMPREF0837_RS07345	Not Available	Negative	1412320 - 1414560	84594.1
comea family dna-binding protein	HMPREF0837_RS07350	Not Available	Negative	1414544 - 1415194	23231.9
gnat family n-acetyltransferase	HMPREF0837_RS07355	Not Available	Negative	1415262 - 1415831	21557.8
hypothetical protein	HMPREF0837_RS13025	Not Available	Positive	1416008 - 1417119	38964.3
hypothetical protein	HMPREF0837_RS07375	Not Available	Negative	1417420 - 1417746	12284.1
gnat family n-acetyltransferase	HMPREF0837_RS07380	Not Available	Negative	1417749 - 1418249	19021.8