Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
gtpase era	HMPREF0837_RS07275	Not Available	Negative	1400414 - 1401313	34012.4
diacylglycerol kinase family protein	HMPREF0837_RS07280	Not Available	Negative	1401330 - 1401725	14803.4
rrna maturation rnase ybey	HMPREF0837_RS07285	Not Available	Negative	1401706 - 1402203	19246.4
rqc2 family fibronectin-binding protein pava	HMPREF0837_RS07290	Not Available	Positive	1402308 - 1403963	63340.0
endo-beta-n-acetylglucosaminidase	HMPREF0837_RS07295	Not Available	Negative	1404024 - 1406189	84355.7
dihydroorotate dehydrogenase	HMPREF0837_RS07300	Not Available	Negative	1406231 - 1407169	33140.2
dihydroorotate dehydrogenase electron transfer subunit	HMPREF0837_RS07305	Not Available	Negative	1407180 - 1407980	28885.0
voc family protein	HMPREF0837_RS07310	Not Available	Negative	1408230 - 1408610	14438.9
50s ribosomal protein l20	HMPREF0837_RS07315	Not Available	Negative	1408668 - 1409027	13694.0
50s ribosomal protein l35	HMPREF0837_RS07320	Not Available	Negative	1409079 - 1409279	7836.78