Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
nudix hydrolase	HMPREF0837_RS07175	Not Available	Negative	1382862 - 1383407	20515.5
bifunctional udp-n-acetylglucosamine diphosphorylase/glucosamine-1-phosphate n-acetyltransferase glmu	HMPREF0837_RS07180	Not Available	Negative	1383417 - 1384796	49376.6
gh25 family lysozyme	HMPREF0837_RS07185	Not Available	Positive	1384940 - 1385728	29643.2
duf368 domain-containing protein	HMPREF0837_RS07190	Not Available	Positive	1385823 - 1386665	30616.3
aminoacyl-trna deacylase	HMPREF0837_RS07195	Not Available	Positive	1386665 - 1387147	17583.7
histidine phosphatase family protein	HMPREF0837_RS07200	Not Available	Positive	1387147 - 1387767	23335.9
hypothetical protein	HMPREF0837_RS12425	Not Available	Negative	1388020 - 1388115	3823.72
hypothetical protein	HMPREF0837_RS07210	Not Available	Positive	1388528 - 1388869	13401.9
peptidylprolyl isomerase prsa	HMPREF0837_RS07215	Not Available	Negative	1388986 - 1389927	34441.3
o-methyltransferase	HMPREF0837_RS07220	Not Available	Negative	1389995 - 1390708	26917.7