Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
thiol-disulfide oxidoreductase-associated membrane protein ccda2	HMPREF0837_RS07115	Not Available	Negative	1374719 - 1375426	25891.8
egfr-like transmembrane domain-containing protein	HMPREF0837_RS07120	Not Available	Negative	1375657 - 1376073	15137.2
hypothetical protein	HMPREF0837_RS07125	Not Available	Negative	1376098 - 1376298	6959.06
hypothetical protein	HMPREF0837_RS11840	Not Available	Negative	1376465 - 1377093	23427.5
hypothetical protein	HMPREF0837_RS11850	Not Available	Positive	1377371 - 1378697	48514.8
glycerophosphoryl diester phosphodiesterase membrane domain-containing protein	HMPREF0837_RS07150	Not Available	Negative	1378799 - 1380562	68869.1
3'-5' exonuclease	HMPREF0837_RS07155	Not Available	Negative	1380571 - 1381161	22189.8
chromosome segregation protein rocs	HMPREF0837_RS07160	Not Available	Negative	1381259 - 1381750	18971.7
5'-methylthioadenosine/adenosylhomocysteine nucleosidase	HMPREF0837_RS07165	Not Available	Negative	1381827 - 1382519	24702.4
cell wall synthase accessory phosphoprotein macp	HMPREF0837_RS07170	Not Available	Negative	1382536 - 1382850	11809.5