Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
serine hydroxymethyltransferase	HMPREF0837_RS06960	Not Available	Negative	1343204 - 1344460	45260.8
gnat family n-acetyltransferase	HMPREF0837_RS06965	Not Available	Negative	1344522 - 1344953	16018.0
l-threonylcarbamoyladenylate synthase	HMPREF0837_RS06970	Not Available	Negative	1344955 - 1345557	22334.8
peptide chain release factor n(5)-glutamine methyltransferase	HMPREF0837_RS06975	Not Available	Negative	1345541 - 1346380	31607.2
peptide chain release factor 1	HMPREF0837_RS06980	Not Available	Negative	1346380 - 1347459	40648.0
thymidine kinase	HMPREF0837_RS06985	Not Available	Negative	1347456 - 1348046	22503.1
4-oxalocrotonate tautomerase	HMPREF0837_RS06990	Not Available	Positive	1348170 - 1348352	6747.18
trna uridine-5-carboxymethylaminomethyl(34) synthesis gtpase mnme	HMPREF0837_RS06995	Not Available	Positive	1348488 - 1349861	50518.9
4-hydroxy-tetrahydrodipicolinate synthase	HMPREF0837_RS07000	Not Available	Negative	1349908 - 1350843	33911.6
aspartate-semialdehyde dehydrogenase	HMPREF0837_RS07005	Not Available	Negative	1350899 - 1351975	38949.7