Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
glycosyltransferase family 4 protein	HMPREF0837_RS06750	Not Available	Negative	1302938 - 1304263	50369.6
alpha-galactosylglucosyldiacylglycerol synthase	HMPREF0837_RS06755	Not Available	Negative	1304279 - 1305322	39941.7
metal-sulfur cluster assembly factor	HMPREF0837_RS06760	Not Available	Negative	1305437 - 1305766	12387.0
rna polymerase sigma factor rpod	HMPREF0837_RS06765	Not Available	Negative	1305780 - 1306889	42033.1
dna primase	HMPREF0837_RS06770	Not Available	Negative	1306892 - 1308652	67262.2
abc transporter atp-binding protein	HMPREF0837_RS06775	Not Available	Negative	1308742 - 1309500	28353.7
abc transporter permease	HMPREF0837_RS06780	Not Available	Negative	1309497 - 1310363	30402.6
tryptophan abc transporter substrate-binding protein	HMPREF0837_RS06785	Not Available	Negative	1310432 - 1311436	35104.3
phosphoenolpyruvate carboxylase	HMPREF0837_RS06790	Not Available	Negative	1311849 - 1314545	103286.0
cell division peptidoglycan polymerase ftsw	HMPREF0837_RS06795	Not Available	Negative	1314565 - 1315794	45467.9