Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
nadp-dependent glyceraldehyde-3-phosphate dehydrogenase	HMPREF0837_RS06515	Not Available	Negative	1262403 - 1263827	51113.5
type i pullulanase	HMPREF0837_RS06525	Not Available	Negative	1264371 - 1266650	86601.8
nad-dependent dna ligase liga	HMPREF0837_RS06530	Not Available	Negative	1266762 - 1268720	72307.9
mfs transporter	HMPREF0837_RS06535	Not Available	Negative	1268813 - 1269991	43405.3
xre/mutr family transcriptional regulator	HMPREF0837_RS06540	Not Available	Negative	1270071 - 1270934	34123.5
abc-f family atp-binding cassette domain-containing protein	HMPREF0837_RS06545	Not Available	Negative	1270937 - 1272838	72029.3
hu family dna-binding protein	HMPREF0837_RS06550	Not Available	Negative	1273265 - 1273540	9650.64
degv family protein	HMPREF0837_RS06555	Not Available	Negative	1273647 - 1274486	30704.1
yitt family protein	HMPREF0837_RS06560	Not Available	Positive	1274628 - 1275476	31283.3
bifunctional riboflavin kinase/fad synthetase	HMPREF0837_RS06565	Not Available	Negative	1275569 - 1276486	34524.4