Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
hypothetical protein	HMPREF0837_RS11780	Not Available	Positive	1252280 - 1252423	5360.53
surface-displayed alpha-enolase	HMPREF0837_RS06470	Not Available	Negative	1252561 - 1253865	47105.6
yuei family protein	HMPREF0837_RS06475	Not Available	Positive	1254029 - 1254475	17094.4
glycerate kinase	HMPREF0837_RS06480	Not Available	Negative	1254472 - 1255587	39261.4
had family hydrolase	HMPREF0837_RS12690	Not Available	Negative	1255701 - 1255925	8255.32
had-ib family phosphatase	HMPREF0837_RS12695	Not Available	Negative	1255870 - 1256241	13491.6
glycogen synthase glga	HMPREF0837_RS06495	Not Available	Negative	1256300 - 1257733	54134.7
glucose-1-phosphate adenylyltransferase subunit glgd	HMPREF0837_RS06500	Not Available	Negative	1257730 - 1258869	42583.6
glucose-1-phosphate adenylyltransferase	HMPREF0837_RS06505	Not Available	Negative	1258859 - 1260001	41492.9
1,4-alpha-glucan branching protein glgb	HMPREF0837_RS06510	Not Available	Negative	1259991 - 1261919	75609.5