Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
tagatose-6-phosphate kinase	HMPREF0837_RS06280	Not Available	Positive	1199861 - 1200790	33402.0
tagatose-bisphosphate aldolase	HMPREF0837_RS06285	Not Available	Positive	1200792 - 1201772	36360.0
prd domain-containing protein	HMPREF0837_RS06290	Not Available	Positive	1202006 - 1202842	33014.5
pts lactose/cellobiose transporter subunit iia	HMPREF0837_RS06295	Not Available	Positive	1202878 - 1203195	11513.8
lactose-specific pts transporter subunit eiic	HMPREF0837_RS06300	Not Available	Positive	1203195 - 1204886	61108.1
6-phospho-beta-galactosidase	HMPREF0837_RS06305	Not Available	Positive	1205101 - 1206507	53930.0
duf3884 family protein	HMPREF0837_RS06310	Not Available	Positive	1206550 - 1206807	10222.9
deor/glpr family dna-binding transcription regulator	HMPREF0837_RS06315	Not Available	Negative	1207086 - 1207847	28433.3
class 1b ribonucleoside-diphosphate reductase subunit beta	HMPREF0837_RS06320	Not Available	Negative	1208029 - 1208991	36978.3
class 1b ribonucleoside-diphosphate reductase subunit alpha	HMPREF0837_RS06325	Not Available	Negative	1209179 - 1211338	81596.8