Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
gnat family n-acetyltransferase	HMPREF0837_RS06065	Not Available	Positive	1163870 - 1164337	18113.0
8-oxo-dgtp diphosphatase	HMPREF0837_RS06070	Not Available	Positive	1164410 - 1164877	17961.1
transcription repressor nadr	HMPREF0837_RS06075	Not Available	Negative	1164874 - 1165389	19611.4
ecf transporter s component	HMPREF0837_RS06080	Not Available	Negative	1165401 - 1165928	19433.7
ecf transporter s component	HMPREF0837_RS06085	Not Available	Negative	1166224 - 1166787	20274.0
phosphopantothenoylcysteine decarboxylase	HMPREF0837_RS06090	Not Available	Negative	1166771 - 1167322	19897.3
phosphopantothenate--cysteine ligase	HMPREF0837_RS06095	Not Available	Negative	1167334 - 1168023	25830.3
formate--tetrahydrofolate ligase	HMPREF0837_RS06100	Not Available	Positive	1168253 - 1169923	59589.1
a/g-specific adenine glycosylase	HMPREF0837_RS06105	Not Available	Positive	1170252 - 1171427	45237.3
response regulator yycf	HMPREF0837_RS06110	Not Available	Positive	1171482 - 1172186	26817.2