Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
duf6110 family protein	HMPREF0837_RS00575	Not Available	Negative	97504 - 97782	10046.2
putative rna methyltransferase	HMPREF0837_RS00580	Not Available	Positive	97934 - 98782	32014.1
hypothetical protein	HMPREF0837_RS12815	Not Available	Negative	99343 - 99549	8293.3
glycogen/starch/alpha-glucan family phosphorylase	HMPREF0837_RS00600	Not Available	Negative	100504 - 102762	85158.7
hypothetical protein	HMPREF0837_RS00605	Not Available	Negative	102788 - 104320	58577.8
maltodextrin abc transporter substrate-binding protein	HMPREF0837_RS00610	Not Available	Positive	104855 - 106126	45427.5
carbohydrate abc transporter permease	HMPREF0837_RS00615	Not Available	Positive	106237 - 107529	47775.4
sugar abc transporter permease	HMPREF0837_RS00620	Not Available	Positive	107531 - 108373	31509.4
duf1189 domain-containing protein	HMPREF0837_RS00625	Not Available	Positive	108626 - 109426	30685.3
laci family dna-binding transcriptional regulator	HMPREF0837_RS00630	Not Available	Positive	109436 - 110422	37045.6