Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
chromosome segregation protein smc	HMPREF0837_RS06015	Not Available	Positive	1149096 - 1152635	134158.0
cof-type had-iib family hydrolase	HMPREF0837_RS06020	Not Available	Positive	1152632 - 1153426	29550.3
cof-type had-iib family hydrolase	HMPREF0837_RS06025	Not Available	Positive	1153426 - 1154244	30298.0
signal recognition particle-docking protein ftsy	HMPREF0837_RS06030	Not Available	Positive	1154248 - 1155537	47902.6
glucose-6-phosphate dehydrogenase	HMPREF0837_RS06035	Not Available	Negative	1155581 - 1157068	56750.8
amino acid abc transporter atp-binding protein	HMPREF0837_RS06040	Not Available	Negative	1157217 - 1157957	27353.9
abc transporter substrate-binding protein/permease	HMPREF0837_RS06045	Not Available	Negative	1157957 - 1160122	78376.0
cpbp family intramembrane glutamic endopeptidase	HMPREF0837_RS06050	Not Available	Positive	1160292 - 1161245	35327.7
excinuclease abc subunit uvrb	HMPREF0837_RS06055	Not Available	Positive	1161322 - 1163310	75791.3
gnat family n-acetyltransferase	HMPREF0837_RS06060	Not Available	Positive	1163320 - 1163883	22445.8