Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
endonuclease iii	HMPREF0837_RS05860	Not Available	Positive	1118107 - 1118736	23278.2
bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase pyrr	HMPREF0837_RS05865	Not Available	Positive	1118947 - 1119468	19609.7
aspartate carbamoyltransferase catalytic subunit	HMPREF0837_RS05870	Not Available	Positive	1119487 - 1120410	34708.2
carbamoyl phosphate synthase small subunit	HMPREF0837_RS05875	Not Available	Positive	1120460 - 1121539	39865.6
carbamoyl-phosphate synthase large subunit	HMPREF0837_RS05880	Not Available	Positive	1121852 - 1125028	116065.0
phosphorylcholine transferase licd	HMPREF0837_RS05885	Not Available	Negative	1125303 - 1126112	32141.6
phosphorylcholine transferase licd	HMPREF0837_RS05890	Not Available	Negative	1126114 - 1126917	31908.1
type iv teichoic acid flippase tacf	HMPREF0837_RS05895	Not Available	Negative	1126927 - 1128414	56553.7
2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase	HMPREF0837_RS05900	Not Available	Positive	1128750 - 1129457	26257.8
ribitol-5-phosphate dehydrogenase	HMPREF0837_RS05905	Not Available	Positive	1129462 - 1130484	38772.8