Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
duf1934 domain-containing protein	HMPREF0837_RS05815	Not Available	Positive	1108853 - 1109230	15034.0
putative dna-binding protein	HMPREF0837_RS05820	Not Available	Positive	1109321 - 1109653	13347.8
signal recognition particle protein	HMPREF0837_RS05825	Not Available	Positive	1109665 - 1111236	57786.9
uracil-xanthine permease family protein	HMPREF0837_RS05830	Not Available	Negative	1111431 - 1112714	44806.2
16s rrna (guanine(527)-n(7))-methyltransferase rsmg	HMPREF0837_RS05835	Not Available	Negative	1112968 - 1113681	27200.0
lema family protein	HMPREF0837_RS05840	Not Available	Positive	1113775 - 1114335	20620.7
zinc metalloprotease htpx	HMPREF0837_RS05845	Not Available	Positive	1114337 - 1115236	32812.3
atp-binding cassette domain-containing protein	HMPREF0837_RS05850	Not Available	Negative	1115280 - 1116806	58132.9
hypothetical protein	HMPREF0837_RS13300	Not Available	Negative	1117079 - 1117443	13476.4
yced family protein	HMPREF0837_RS05855	Not Available	Positive	1117565 - 1118107	20385.8