Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
abc transporter permease	HMPREF0837_RS05565	Not Available	Positive	1057331 - 1058104	28979.9
abc transporter substrate-binding protein	HMPREF0837_RS05570	Not Available	Positive	1058101 - 1059171	41013.8
hypothetical protein	HMPREF0837_RS05575	Not Available	Positive	1059416 - 1059655	9373.74
lurp-one-related/scramblase family protein	HMPREF0837_RS05580	Not Available	Positive	1059930 - 1060415	18802.6
alanine--trna ligase	HMPREF0837_RS05585	Not Available	Positive	1060437 - 1063055	96435.3
alpha-amylase	HMPREF0837_RS05590	Not Available	Negative	1063145 - 1064599	55920.7
abc transporter atp-binding protein	HMPREF0837_RS05595	Not Available	Positive	1064778 - 1065527	27648.2
hypothetical protein	HMPREF0837_RS05600	Not Available	Positive	1065508 - 1067142	61541.7
class i sam-dependent rrna methyltransferase	HMPREF0837_RS05605	Not Available	Positive	1067827 - 1068990	43872.0
type i 3-dehydroquinate dehydratase	HMPREF0837_RS05610	Not Available	Positive	1068987 - 1069664	25696.8