Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
nad(p)h-dependent glycerol-3-phosphate dehydrogenase	HMPREF0837_RS00525	Not Available	Positive	85175 - 86191	36778.8
utp--glucose-1-phosphate uridylyltransferase galu	HMPREF0837_RS00530	Not Available	Positive	86213 - 87112	33251.0
rhomboid family intramembrane serine protease	HMPREF0837_RS00535	Not Available	Negative	87184 - 87861	25064.4
5-formyltetrahydrofolate cyclo-ligase	HMPREF0837_RS00540	Not Available	Negative	87845 - 88384	20530.5
n-acetyldiaminopimelate deacetylase	HMPREF0837_RS00545	Not Available	Negative	88396 - 89526	41593.9
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate n-acetyltransferase	HMPREF0837_RS00550	Not Available	Negative	89594 - 90292	23920.1
dmt family transporter	HMPREF0837_RS00555	Not Available	Negative	90522 - 91433	33648.3
penicillin-binding protein pbp1b	HMPREF0837_RS00560	Not Available	Negative	91498 - 93963	89555.8
tyrosine--trna ligase	HMPREF0837_RS00565	Not Available	Positive	94105 - 95361	47492.4
heavy metal translocating p-type atpase	HMPREF0837_RS00570	Not Available	Negative	95439 - 97502	77611.1