Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
phosphate abc transporter atp-binding protein pstb	HMPREF0837_RS05515	Not Available	Positive	1048132 - 1048935	30364.4
phosphate abc transporter atp-binding protein pstb	HMPREF0837_RS05520	Not Available	Positive	1048948 - 1049706	27955.5
phosphate signaling complex protein phou	HMPREF0837_RS05525	Not Available	Positive	1049718 - 1050371	25029.8
abc transporter substrate-binding protein	HMPREF0837_RS05530	Not Available	Positive	1050528 - 1051343	29307.0
plp-dependent aminotransferase family protein	HMPREF0837_RS05535	Not Available	Negative	1051363 - 1052634	49417.9
acetolactate decarboxylase	HMPREF0837_RS05540	Not Available	Positive	1052776 - 1053507	27344.5
yhfc family intramembrane metalloprotease	HMPREF0837_RS05545	Not Available	Positive	1053517 - 1054269	28242.7
udp-n-acetylmuramate dehydrogenase	HMPREF0837_RS05550	Not Available	Positive	1054381 - 1055331	34540.8
abc transporter atp-binding protein	HMPREF0837_RS05555	Not Available	Positive	1055390 - 1056547	44149.9
abc transporter permease	HMPREF0837_RS05560	Not Available	Positive	1056528 - 1057334	30661.1