Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
acyl-[acyl-carrier-protein] thioesterase	HMPREF0837_RS05465	Not Available	Positive	1039793 - 1040530	28392.4
tigr01457 family had-type hydrolase	HMPREF0837_RS05470	Not Available	Positive	1040541 - 1041314	28239.8
tigr01906 family membrane protein	HMPREF0837_RS05475	Not Available	Positive	1041304 - 1041921	24102.2
spx/mgsr family rna polymerase-binding regulatory protein	HMPREF0837_RS05480	Not Available	Positive	1042131 - 1042532	15451.0
upf0223 family protein	HMPREF0837_RS05485	Not Available	Positive	1042532 - 1042810	10308.2
inositol monophosphatase family protein	HMPREF0837_RS05490	Not Available	Positive	1042800 - 1043573	28777.5
rsmf rrna methyltransferase first c-terminal domain-containing protein	HMPREF0837_RS05495	Not Available	Positive	1043574 - 1044878	48162.7
phosphate abc transporter substrate-binding protein psts	HMPREF0837_RS05500	Not Available	Positive	1045452 - 1046330	31203.0
phosphate abc transporter permease subunit pstc	HMPREF0837_RS05505	Not Available	Positive	1046330 - 1047247	32697.3
phosphate abc transporter permease psta	HMPREF0837_RS05510	Not Available	Positive	1047237 - 1048121	31621.1