Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
n-acetylmuramoyl-l-alanine amidase family protein	HMPREF0837_RS13295	Not Available	Positive	1030979 - 1031368	14566.9
is1380-like element isspn5 family transposase	HMPREF0837_RS05420	Not Available	Positive	1031592 - 1032938	51934.2
trna preq1(34) s-adenosylmethionine ribosyltransferase-isomerase quea	HMPREF0837_RS05425	Not Available	Negative	1033737 - 1034765	38381.9
glucosamine-6-phosphate deaminase	HMPREF0837_RS05430	Not Available	Positive	1034916 - 1035623	25731.3
30s ribosomal protein s21	HMPREF0837_RS05435	Not Available	Positive	1035763 - 1035939	6998.6
hpr(ser) kinase/phosphatase	HMPREF0837_RS05440	Not Available	Positive	1036069 - 1037004	34729.2
prolipoprotein diacylglyceryl transferase	HMPREF0837_RS05445	Not Available	Positive	1036997 - 1037785	30294.5
duf948 domain-containing protein	HMPREF0837_RS05450	Not Available	Positive	1037786 - 1038169	13693.9
ytxh domain-containing protein	HMPREF0837_RS05455	Not Available	Positive	1038185 - 1038574	14291.6
radical sam family heme chaperone hemw	HMPREF0837_RS05460	Not Available	Positive	1038658 - 1039788	42751.3