Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
chy zinc finger protein	HMPREF0837_RS11710	Not Available	Positive	1021876 - 1022187	12287.0
hypothetical protein	HMPREF0837_RS05370	Not Available	Positive	1022447 - 1023175	27524.5
abc transporter atp-binding protein	HMPREF0837_RS05375	Not Available	Positive	1023566 - 1024402	31291.8
abc transporter permease	HMPREF0837_RS05380	Not Available	Positive	1024418 - 1025146	27514.0
helix-turn-helix transcriptional regulator	HMPREF0837_RS05385	Not Available	Positive	1025532 - 1025741	7752.42
duf6773 family protein	HMPREF0837_RS05390	Not Available	Positive	1025731 - 1026219	19204.4
nicotinate phosphoribosyltransferase	HMPREF0837_RS05395	Not Available	Positive	1026335 - 1027795	55111.7
ammonia-dependent nad(+) synthetase	HMPREF0837_RS05400	Not Available	Positive	1027792 - 1028616	30136.8
gnat family n-acetyltransferase	HMPREF0837_RS05405	Not Available	Positive	1028966 - 1029517	20845.9
g5 domain-containing protein	HMPREF0837_RS13290	Not Available	Positive	1030563 - 1030925	13068.5