Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
helix-turn-helix domain-containing protein	HMPREF0837_RS05310	Not Available	Negative	1009666 - 1010658	38456.6
abc transporter atp-binding protein	HMPREF0837_RS05315	Not Available	Positive	1010818 - 1012572	65779.8
abc transporter atp-binding protein	HMPREF0837_RS05320	Not Available	Positive	1012556 - 1014277	64789.0
mptd family putative ecf transporter s component	HMPREF0837_RS05325	Not Available	Positive	1014288 - 1014872	21662.1
energy-coupling factor transporter transmembrane component t family protein	HMPREF0837_RS05330	Not Available	Positive	1014872 - 1015567	26029.3
abc transporter atp-binding protein	HMPREF0837_RS05335	Not Available	Positive	1015555 - 1016919	51782.4
hypothetical protein	HMPREF0837_RS12365	Not Available	Negative	1017374 - 1018032	23607.5
dna-methyltransferase	HMPREF0837_RS05350	Not Available	Negative	1018207 - 1019397	45784.1
hypothetical protein	HMPREF0837_RS11700	Not Available	Negative	1019394 - 1019978	22211.5
peptidase u32 family protein	HMPREF0837_RS05365	Not Available	Positive	1020575 - 1021861	47941.2