Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
duf1836 domain-containing protein	HMPREF0837_RS05195	Not Available	Negative	993057 - 993503	16905.2
gnat family n-acetyltransferase	HMPREF0837_RS05200	Not Available	Positive	993638 - 994132	18297.6
methylated-dna--[protein]-cysteine s-methyltransferase	HMPREF0837_RS05205	Not Available	Positive	994132 - 994662	19728.7
arsenate reductase family protein	HMPREF0837_RS05210	Not Available	Positive	994656 - 995012	13388.2
amino acid abc transporter permease	HMPREF0837_RS05215	Not Available	Positive	995170 - 995970	28932.9
amino acid abc transporter atp-binding protein	HMPREF0837_RS05220	Not Available	Positive	995970 - 996713	27387.0
duf4059 family protein	HMPREF0837_RS05225	Not Available	Positive	996791 - 997015	8286.82
thioredoxin-disulfide reductase	HMPREF0837_RS05230	Not Available	Positive	997081 - 997992	33177.2
23s rrna (guanosine(2251)-2'-o)-methyltransferase rlmb	HMPREF0837_RS05235	Not Available	Negative	998030 - 998758	26492.0
peptide deformylase	HMPREF0837_RS05240	Not Available	Negative	998803 - 999414	22677.4