Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
glycine--trna ligase subunit alpha	HMPREF0837_RS05145	Not Available	Positive	982631 - 983548	34936.1
glycine--trna ligase subunit beta	HMPREF0837_RS05150	Not Available	Positive	983808 - 985844	75442.5
duf896 family protein	HMPREF0837_RS05155	Not Available	Positive	985886 - 986143	9873.76
nad(p)h-dependent oxidoreductase	HMPREF0837_RS05160	Not Available	Negative	986260 - 987504	45839.8
nadph-dependent fmn reductase	HMPREF0837_RS05165	Not Available	Negative	987522 - 988127	22560.4
fad:protein fmn transferase	HMPREF0837_RS05170	Not Available	Negative	988187 - 989110	33817.4
h2o-forming nadh oxidase	HMPREF0837_RS05175	Not Available	Positive	989404 - 990783	50258.1
pyridoxal 5'-phosphate synthase lyase subunit pdxs	HMPREF0837_RS05180	Not Available	Positive	990935 - 991810	31742.6
pyridoxal 5'-phosphate synthase glutaminase subunit pdxt	HMPREF0837_RS05185	Not Available	Positive	991811 - 992392	21095.7
paqr family membrane homeostasis protein trha	HMPREF0837_RS05190	Not Available	Negative	992413 - 993060	24175.4