Streptococcus pneumoniae TCH8431/19A

Gram-positiveCocciNon-motileFacultative

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

A Gram-positive nonmotile bacterium, Streptococcus pneumoniae is the most common bacterial cause of acute respiratory infection and otitis media, and is estimated to result in over 1 millions deaths in children, the elderly, debilitated and immunosuppressed people every year. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones. Strain AP200 is a clinical strain isolated in Italy in 2003 from the cerebrospinal fluid of a patient with meningitis. It is serotype 11A and sequence type (ST) 2003, which is a single-locus variant of ST62. It is resistant to erythromycin, inducibly resistant to clindamycin and susceptible to penicillin and tetracycline (adapted from PMID 18070957). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Bacillota
Class	Bacilli
Order	Lactobacillales
Family	Streptococcaceae
Genus	Streptococcus
Species	Streptococcus pneumoniae
Strain	TCH8431/19A

Profile

Physiology
Gram staining properties	Positive
Shape	Cocci
Mobility	No
Flagellar presence	Yes
Number of membranes	1

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Facultative
Optimal temperature	30
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Homo sapiens, Metazoa
Cell arrangement	Chains-Pairs
Sporulation	Nonsporulating
Energy source	Not Available
Pathogenicity	Yes

Genome Summary

Streptococcus pneumoniae TCH8431/19A, complete sequence.

NC_014251.1

Gene Summary

Adenine Count

625910 bp

Thymine Count

630791 bp

Guanine Count

414099 bp

Cytosine Count

417972 bp

Genome Length

2088772 bp

Protein-coding Genes

2085 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
response regulator transcription factor	HMPREF0837_RS00480	Not Available	Positive	77627 - 78334	27232.2
two-component system histidine kinase pnps	HMPREF0837_RS00485	Not Available	Positive	78335 - 79666	49729.2
substrate-binding domain-containing protein	HMPREF0837_RS00490	Not Available	Positive	79833 - 80708	30758.5
phosphate abc transporter permease subunit pstc	HMPREF0837_RS00495	Not Available	Positive	80826 - 81689	30723.6
phosphate abc transporter permease psta	HMPREF0837_RS00500	Not Available	Positive	81682 - 82497	29132.0
phosphate abc transporter atp-binding protein pstb	HMPREF0837_RS00505	Not Available	Positive	82499 - 83251	28095.8
phosphate signaling complex protein phou	HMPREF0837_RS00510	Not Available	Positive	83266 - 83916	24193.3
hypothetical protein	HMPREF0837_RS00515	Not Available	Positive	83957 - 84409	17433.3
hypothetical protein	HMPREF0837_RS13385	Not Available	Negative	84524 - 84658	5492.55
hypothetical protein	HMPREF0837_RS13390	Not Available	Negative	84847 - 84963	4662.71