Corynebacterium urealyticum DSM 7109

Gram-positiveRodNon-motileAerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Corynebacteriaceae

Genus

Corynebacterium

Description

Bacteria from the genus Corynebacterium are Gram-positive, nonmotile rods. C.urealyticum is a strictly aerobic, lipid-requiring, urealytic bacterium of the human skin flora that causes urinary tract infections; strain DSM 7109 was recovered from a patient with alkaline-encrusted cystitis. Metabolic analysis of the lipid-requiring phenotype revealed the absence of a fatty acid synthase gene and the presence of a beta-oxidation pathway along with a large repertoire of auxillary genes for the degradation of exogenous fatty acids. A urease locus may play a pivotal role in virulence of C. urealyticum by the alkalinization of human urine and the formation of struvite stones. Multidrug resistance in DSM 7109 is mediated by transposable elements, conferring resistances to macrolides, lincosamides, ketolides, aminoglycosides, chloramphenicol, and tetracycline (modified from PubMed 18367281). (EBI Integr8)

Taxonomy

Kingdom	Bacillati
Phylum	Actinomycetota
Class	Actinomycetes
Order	Mycobacteriales
Family	Corynebacteriaceae
Genus	Corynebacterium
Species	Corynebacterium urealyticum
Strain	DSM 7109

Profile

Physiology
Gram staining properties	Positive
Shape	Rod
Mobility	No
Flagellar presence	Yes
Number of membranes	1

AI-generated image based on bacteria physiology

Ecology, Host, and Life Cycle
Oxygen requirements	Aerobe
Optimal temperature	37
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Not Available
Cell arrangement	Singles
Sporulation	Nonsporulating
Energy source	Chemoorganotroph
Pathogenicity	Yes

Genome Summary

Corynebacterium urealyticum DSM 7109, complete sequence.

NC_010545.1

Gene Summary

Adenine Count

428363 bp

Thymine Count

420167 bp

Guanine Count

757668 bp

Cytosine Count

763021 bp

Genome Length

2369219 bp

Protein-coding Genes

1990 genes

Non-Coding Genes

77 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
Trna-tyr	Not Available	Not Available	Positive	329803 - 329885	Not Available
hypothetical protein	CU_RS01335	Not Available	Positive	330339 - 330734	13358.1
dead/deah box helicase family protein	CU_RS01340	Not Available	Negative	330883 - 334563	136309.0
restriction endonuclease subunit s	CU_RS01345	Not Available	Negative	334718 - 335872	41814.8
class i sam-dependent dna methyltransferase	CU_RS01350	Not Available	Negative	335872 - 337446	59122.7
type 1 glutamine amidotransferase domain-containing protein	CU_RS01355	Not Available	Positive	337552 - 338085	18620.6
spfh domain-containing protein	CU_RS01360	Not Available	Negative	338198 - 338974	28477.0
Trna-thr	Not Available	Not Available	Positive	339484 - 339556	Not Available
Trna-met	Not Available	Not Available	Positive	339624 - 339697	Not Available
Trna-trp	Not Available	Not Available	Positive	339983 - 340055	Not Available

Displaying genes 291 – 300 of 2067 in total

Pathways

1196 pathways

2,3-Dihydroxybenzoate Biosynthesis

Biosynthesis of Siderophore Group Nonribosomal Peptides

Cysteine Biosynthesis

Glycine Biosynthesis

Show All 1196 Pathways

Metabolite ID	Metabolite name	CAS number	Average mass Monoisotopic mass
BASm0000387	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6	Not available	Average455.432Da Monoisotopic455.1564286Da
BASm0001865	diphosphateHO7P2	Not available	Average174.95Da Monoisotopic174.9213971Da
BASm0002305	(S)-2-ethyl-2-hydroxy-3-oxobutanoateC6H9O4	Not available	Average145.135Da Monoisotopic145.0506324Da
BASm0002307	(2R,3R)-2,3-dihydroxy-3-methylpentanoateC6H11O4	Not available	Average147.1491Da Monoisotopic147.06573384Da
BASm0002458	1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranosideC14H25NO11	Not available	Average383.35Da Monoisotopic383.142760629Da
BASm0002751	(S)-4-amino-5-oxopentanoateC5H9NO3	Not available	Average131.1299Da Monoisotopic131.0582432Da
BASm0002826	(2R)-3-phospho-glyceroyl phosphateC3H4O10P2	Not available	Average262.005Da Monoisotopic261.9301646Da
BASm0002833	FMNH2C17H21N4O9P	`5666-16-0`	Average456.3438Da Monoisotopic456.1046148Da
BASm0002858	all-trans-undecaprenyl phosphateC55H89O4P	Not available	Average845.288Da Monoisotopic844.6509455Da
BASm0002909	O-acetyl-L-homoserineC6H11NO4	`7540-67-2`	Average161.1558Da Monoisotopic161.0688078Da