Corynebacterium urealyticum DSM 7109

Gram-positiveRodNon-motileAerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Corynebacteriaceae

Genus

Corynebacterium

Description

Bacteria from the genus Corynebacterium are Gram-positive, nonmotile rods. C.urealyticum is a strictly aerobic, lipid-requiring, urealytic bacterium of the human skin flora that causes urinary tract infections; strain DSM 7109 was recovered from a patient with alkaline-encrusted cystitis. Metabolic analysis of the lipid-requiring phenotype revealed the absence of a fatty acid synthase gene and the presence of a beta-oxidation pathway along with a large repertoire of auxillary genes for the degradation of exogenous fatty acids. A urease locus may play a pivotal role in virulence of C. urealyticum by the alkalinization of human urine and the formation of struvite stones. Multidrug resistance in DSM 7109 is mediated by transposable elements, conferring resistances to macrolides, lincosamides, ketolides, aminoglycosides, chloramphenicol, and tetracycline (modified from PubMed 18367281). (EBI Integr8)

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyCorynebacteriaceae
GenusCorynebacterium
SpeciesCorynebacterium urealyticum
StrainDSM 7109

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Corynebacterium urealyticum DSM 7109
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityYes

Genome Summary

Corynebacterium urealyticum DSM 7109, complete sequence.

Gene Summary

Adenine Count

428363 bp

Thymine Count

420167 bp

Guanine Count

757668 bp

Cytosine Count

763021 bp

Genome Length

2369219 bp

Protein-coding Genes

1990 genes

Non-Coding Genes

77 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
duf4233 domain-containing proteinCU_RS06915Not AvailableNegative1622140 - 162256815389.6
bifunctional tetrahydrofolate synthase/dihydrofolate synthaseCU_RS06920Not AvailableNegative1622601 - 162423857841.1
valine--trna ligaseCU_RS06925Not AvailableNegative1624235 - 1627021105302.0
malate dehydrogenaseCU_RS06930Not AvailableNegative1627145 - 162814935462.9
hypothetical proteinCU_RS06935Not AvailablePositive1628282 - 162905228432.6
atp-dependent clp protease atp-binding subunit clpxCU_RS06940Not AvailableNegative1629143 - 163041746763.0
atp-dependent clp protease proteolytic subunitCU_RS06945Not AvailableNegative1630586 - 163120622784.2
atp-dependent clp protease proteolytic subunitCU_RS06950Not AvailableNegative1631210 - 163178220586.6
trigger factorCU_RS06955Not AvailableNegative1632032 - 163359456867.7
Trna-proNot AvailableNot AvailablePositive1633931 - 1634004Not Available

Displaying genes 1421 – 1430 of 2067 in total

Metabolites

66 records
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Result columns

Structure search compares stored SMILES, InChI, and InChIKey text. Exact mass must match the stored database value.

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Metabolite IDMetabolite nameStructureCAS number
Average massMonoisotopic mass
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0002305(S)-2-ethyl-2-hydroxy-3-oxobutanoateC6H9O4Chemical structure of (S)-2-ethyl-2-hydroxy-3-oxobutanoateNot available
Average145.135Da
Monoisotopic145.0506324Da
BASm0002307(2R,3R)-2,3-dihydroxy-3-methylpentanoateC6H11O4Chemical structure of (2R,3R)-2,3-dihydroxy-3-methylpentanoateNot available
Average147.1491Da
Monoisotopic147.06573384Da
BASm00024581D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranosideC14H25NO11Chemical structure of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranosideNot available
Average383.35Da
Monoisotopic383.142760629Da
BASm0002751(S)-4-amino-5-oxopentanoateC5H9NO3Chemical structure of (S)-4-amino-5-oxopentanoateNot available
Average131.1299Da
Monoisotopic131.0582432Da
BASm0002826(2R)-3-phospho-glyceroyl phosphateC3H4O10P2Chemical structure of (2R)-3-phospho-glyceroyl phosphateNot available
Average262.005Da
Monoisotopic261.9301646Da
BASm0002833FMNH2C17H21N4O9PChemical structure of FMNH25666-16-0
Average456.3438Da
Monoisotopic456.1046148Da
BASm0002858all-trans-undecaprenyl phosphateC55H89O4PChemical structure of all-trans-undecaprenyl phosphateNot available
Average845.288Da
Monoisotopic844.6509455Da
BASm0002909O-acetyl-L-homoserineC6H11NO4Chemical structure of O-acetyl-L-homoserine7540-67-2
Average161.1558Da
Monoisotopic161.0688078Da

Displaying 1–10 of 66 metabolites

Health Effects

No health effects information available for this bacterium.