Corynebacterium urealyticum DSM 7109

Gram-positiveRodNon-motileAerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Corynebacteriaceae

Genus

Corynebacterium

Description

Bacteria from the genus Corynebacterium are Gram-positive, nonmotile rods. C.urealyticum is a strictly aerobic, lipid-requiring, urealytic bacterium of the human skin flora that causes urinary tract infections; strain DSM 7109 was recovered from a patient with alkaline-encrusted cystitis. Metabolic analysis of the lipid-requiring phenotype revealed the absence of a fatty acid synthase gene and the presence of a beta-oxidation pathway along with a large repertoire of auxillary genes for the degradation of exogenous fatty acids. A urease locus may play a pivotal role in virulence of C. urealyticum by the alkalinization of human urine and the formation of struvite stones. Multidrug resistance in DSM 7109 is mediated by transposable elements, conferring resistances to macrolides, lincosamides, ketolides, aminoglycosides, chloramphenicol, and tetracycline (modified from PubMed 18367281). (EBI Integr8)

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyCorynebacteriaceae
GenusCorynebacterium
SpeciesCorynebacterium urealyticum
StrainDSM 7109

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Corynebacterium urealyticum DSM 7109
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityYes

Genome Summary

Corynebacterium urealyticum DSM 7109, complete sequence.

Gene Summary

Adenine Count

428363 bp

Thymine Count

420167 bp

Guanine Count

757668 bp

Cytosine Count

763021 bp

Genome Length

2369219 bp

Protein-coding Genes

1990 genes

Non-Coding Genes

77 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nicotinate-nucleotide adenylyltransferaseCU_RS06865Not AvailableNegative1609183 - 160983324043.7
glutamate-5-semialdehyde dehydrogenaseCU_RS06870Not AvailableNegative1609885 - 161117445714.2
glutamate 5-kinaseCU_RS06875Not AvailableNegative1611237 - 161241541965.5
gtpase obgeCU_RS06880Not AvailableNegative1612526 - 161404054613.4
50s ribosomal protein l27CU_RS06885Not AvailableNegative1614168 - 16144349428.25
50s ribosomal protein l21CU_RS06890Not AvailableNegative1614498 - 161480010898.3
translation initiation factor if-2 n-terminal domain-containing proteinCU_RS06895Not AvailableNegative1615174 - 1618746131908.0
hypothetical proteinCU_RS06900Not AvailablePositive1619073 - 161985828874.5
nucleoside-diphosphate kinaseCU_RS06905Not AvailableNegative1619939 - 162034914743.5
amp-binding proteinCU_RS06910Not AvailablePositive1620515 - 162203854951.0

Displaying genes 1411 – 1420 of 2067 in total

Metabolites

66 records
Export CSV
Compound search
Mass search
Result columns

Structure search compares stored SMILES, InChI, and InChIKey text. Exact mass must match the stored database value.

Clear
Metabolite IDMetabolite nameStructureCAS number
Average massMonoisotopic mass
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0002305(S)-2-ethyl-2-hydroxy-3-oxobutanoateC6H9O4Chemical structure of (S)-2-ethyl-2-hydroxy-3-oxobutanoateNot available
Average145.135Da
Monoisotopic145.0506324Da
BASm0002307(2R,3R)-2,3-dihydroxy-3-methylpentanoateC6H11O4Chemical structure of (2R,3R)-2,3-dihydroxy-3-methylpentanoateNot available
Average147.1491Da
Monoisotopic147.06573384Da
BASm00024581D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranosideC14H25NO11Chemical structure of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranosideNot available
Average383.35Da
Monoisotopic383.142760629Da
BASm0002751(S)-4-amino-5-oxopentanoateC5H9NO3Chemical structure of (S)-4-amino-5-oxopentanoateNot available
Average131.1299Da
Monoisotopic131.0582432Da
BASm0002826(2R)-3-phospho-glyceroyl phosphateC3H4O10P2Chemical structure of (2R)-3-phospho-glyceroyl phosphateNot available
Average262.005Da
Monoisotopic261.9301646Da
BASm0002833FMNH2C17H21N4O9PChemical structure of FMNH25666-16-0
Average456.3438Da
Monoisotopic456.1046148Da
BASm0002858all-trans-undecaprenyl phosphateC55H89O4PChemical structure of all-trans-undecaprenyl phosphateNot available
Average845.288Da
Monoisotopic844.6509455Da
BASm0002909O-acetyl-L-homoserineC6H11NO4Chemical structure of O-acetyl-L-homoserine7540-67-2
Average161.1558Da
Monoisotopic161.0688078Da

Displaying 1–10 of 66 metabolites

Health Effects

No health effects information available for this bacterium.